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Xolair copay assistance card2/28/2024 Discontinue AVONEX if anaphylaxis or other allergic reactions occur Other allergic reactions have included dyspnea, orolingual edema, skin rash and urticaria. Anaphylaxis has been reported as a rare complication of AVONEX use.Patients should be monitored for signs of hepatic injury The potential risk of AVONEX used in combination with known hepatotoxic drugs or other products (e.g., alcohol) should be considered prior to starting AVONEX, or before starting hepatotoxic drugs. In some cases, these events have occurred in the presence of other drugs that have been associated with hepatic injury. Asymptomatic elevation of hepatic transaminases has also been reported, and in some patients has recurred upon rechallenge with AVONEX. Severe hepatic injury, including cases of hepatic failure, has been reported rarely in patients taking AVONEX.For some of these patients, symptoms of depression improved upon cessation of AVONEX Additionally, there have been postmarketing reports of depression, suicidal ideation, and/or development of new or worsening of other pre-existing psychiatric disorders, including psychosis. Depression and suicide have been reported to occur with increased frequency in patients receiving AVONEX. If a patient develops depression or other severe psychiatric symptoms, cessation of AVONEX therapy should be considered. Patients treated with AVONEX and their caregivers should be advised to report immediately any symptoms of depression, suicidal ideation, and/or psychosis to their prescribing physician.The formerly available lyophilized vial formulation of AVONEX is contraindicated in patients with a history of hypersensitivity to albumin (human)ĭepression, Suicide, and Psychotic Disorders.AVONEX® (interferon beta-1a) is contraindicated in patients with a history of hypersensitivity to natural or recombinant interferon beta, or any other component of the formulation.AVONEX® (interferon beta-1a) is indicated for the treatment of relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.
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